CBD or cannabidiol has now emerged as a popular compound owing to its various medicinal uses that it supposedly has. CBD is one of more than a hundred substances, called cannabinoids, that are found in cannabis plants. CBD, another popular cannabinoid, does not cause the ‘high’ that is associated with THC, and studies have been conducted regarding its impact on various ailments. This brought in to focus such areas of interest as the effect of CBD on the brain. Here’s a look at what we know so far: Here’s a look at what we know so far:
1. How CBD reacts with brain receptors
Because the endocannabinoids act on the CB receptors of the brain, it is possible to understand how CBD interacts with the brain through their interactions with the CB receptors.
It is not completely clear how CBD production affects the brain, but it is well known to modulate the endocannabinoid system (ECS), a system consisting of receptors and other signaling molecules that help regulate many physiological processes. The ECS includes two main types of receptors: ,Two of the there receptors types are known as CB1 and CB2. CB1 receptors are mainly localized in the central nervous system whilst CB2 receptors are mainly located in peripheral nervous and immune systems.
CBD does not have any affinities for these receptors like the THC does in its molecular structure. Rather, it regulates their activity. CBD is believed to have an impact on the ECS indirectly since it boosts the levels of endocannabinoids – internal substances that act upon the receptors. This modulation is relevant for regulation of mood, pain and stress.
2. Possible Positive Influence of CBD on the State of Mind
a. Anxiety Reduction:
The previous research indicates that CBD may help in the reduction of anxiety according to several pieces of research. Some studies show that CBD helps with receptors in the brain and serotonin which has an impact on the mood. A few investigations pointed that CBD can decrease the signs of social phobia, generalized anxiety disorder, and post-traumatic stress disorder (PTSD). But these effects poses questions that need further research to get any concrete information.
b. Improved Sleep:
CBD may also interfere with sleep. Anxiety and stress are some of the common symptoms which are related to insomnia and sleep disorders. Earlier studies indicate that CBD may provide relief from particular sleep disorders such as insomnia. CBD can perhaps improve sleep because its effect on the brain is well-known to reduce mental stress and anxiety.
c. Neuroprotection:
CBD has been found to offer neuroprotection, in other words CBD has the potential of preventing death of brain cells. Some research indicated that CBD might slow down the progress of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s because of its antioxidant and anti-inflammatory capabilities. In doing so, CBD might be neuroprotective, which can help to minimize the effects of free radicals and inflammation regarded as damaging to the brain.
d. Epilepsy Management:
CBD is perhaps the most researched cannabis compound to date and its efficacy in treating epilepsy is supported by the most evidence. Epidiolex which contains a purified form of CBD has been recognised by the FDA as a treatment for some forms of epilepsy. Recent studies of CBD has shown that this product has made significant success on the reduction of the intensity and occurrence of seizures in some patients.
3. Possible risks/relation based side effects
CBD although is considered safe, it has been known to elicit certain unwanted effects in some people. Usual side effects are also the symptoms of anemia, including weakness, weight loss, and loose motions. However, CBD has been known to cause drug interactions with some drugs, and therefore it is recommended to seek advice from a one’s doctor before taking CBD particularly if one is on other medication.
Several investigations have been carried out to establish the effect of cannabidiol on the brain, and although these have revealed what appears to be significant effects, more detailed studies are required. CBD seems to have pros in regards to mental health, sleep, and neuroprotection, though, there is subjective variability. Thus, as in any other case of utilizing any substances, people should remember that it’s always better to turn to CBD with caution and consult health care practitioners to make sure that it is safe and useful for the individual’s condition in question.
All in all, CBD is an intriguing molecule which appears to manifest a functional impact on a number of neurological processes. Perhaps, further advances in research on the matter will help to elucidate its strengths and weaknesses and to come up with more precise therapeutic approaches.